How to Interpret Results

Pharmacogenetic Results: Clinical Implications and Recommendations

These pharmacogenetic clinical implications and recommendations are based on the Clinical Pharmacogenetic Implementation Consortium (CPIC) GuidelinesFDA Table of Pharmacogenetic Associations, and FDA labeling. The pharmacogenetic results and accompanying clinical implications and therapeutic recommendations predict the function of drug metabolizing enzymes, drug transporters, and drug target proteins based on the genetic variants that encode these proteins.

Note: This information is based on genotype alone and does not consider possible phenoconversion. Phenoconversion occurs when a patient is taking a medication that induces or inhibits the drug metabolizing enzyme, which can change the predicted phenotype.

Pharmacogenetic test results, their predicted clinical implications, and recommendations should be used as a tool and one piece of information along with other patient-specific factors (e.g., renal function, hepatic function, sex, environment, comorbid diseases) to make prescribing decisions.

Select the medication below to view associated pharmacogenetic recommendations for your patient’s predicted phenotype:

A-L

M-W